Is there a Cure for Aging?



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Aging is a natural and unavoidable process that no one can avoid. This is how the vast majority of us go about our lives, but geneticist David Sinclair isn't one of them.

He claims that with few easy actions, we can prevent aging and live a longer, healthier life, based on his studies spanning more than two decades.


Sinclair believes that we may soon be able to achieve this with pharmaceuticals that are still being studied, and that we may be able to reverse aging.


The scientist, who holds doctorates from both the University of New South Wales in Australia and the Massachusetts Institute of Technology in the United States, is the director of a Harvard University laboratory that studies the causes of our era.

Countless scientific honors have been bestowed upon him as a result of his efforts. It has also earned him a celebrity, with Time magazine naming him one of the world's 100 most influential people, and he has nearly 200,000 Twitter followers.

In addition to 35 patents, the researcher has started or participated in various biotechnology enterprises, some of which are focused to slowing or preventing aging.


Aging is natural and inevitable and no one will survive it. This is how the vast majority of us approach life, but not geneticist David Sinclair.


Based on his studies spanning more than two decades, he says it is possible to delay aging with some simple habits so that we can enjoy a longer, healthier life.


Sinclair thinks it will soon be possible to do this with drugs, which are still being tested and says it is possible that we will be able to reverse aging.


The scientist, who holds a doctorate from the University of New South Wales in Australia and also from the Massachusetts Institute of Technology in the United States, is in charge of a laboratory at Harvard University that researches the causes of our age.


His work earned him dozens of scientific awards. It has also made him a celebrity, being voted as one of the 100 most influential people in the world by Time magazine and has nearly 200,000 followers on Twitter.


The researcher also holds 35 patents, and has founded or participated in several biotechnology companies, some of which are dedicated to slowing or preventing aging.


Merrill Lynch estimated in 2019 that the industry already had a turnover of $110 billion, and that by 2025 it would reach $600 billion in sales.


Sinclair is also the author of the bestselling book The Cycle of Life: Why We’re Getting Old and Why We Don’t Have to.


Contrary to popular belief, Sinclair says in his book that aging is not inevitable.


The world also believes that we must fundamentally change the way we think about aging: rather than seeing it as a common and natural process, we should treat it as a disease and thus as something that can be cured or even cured.


Only by fundamentally changing our view of aging can humanity dramatically increase life expectancy, Sinclair says.

Otherwise, he says, medical advances will only give us a few more years: “We have to do better.”


Why do we age?


Scientists have identified the nine main causes of aging, and in my research over the past 25 years we have found evidence that one of these causes many, if not all, of the others, and involves a loss of information.


We have two types of information in the body that we inherit from our parents and are affected by environment and time.


One is the “digital” information, the genetic code, and the other is the analog, the epigenome, the systems in the cell that control which genes are turned on and off.


Turning the 20,000 genes on and off in a cell is what tells the cell who it is – and that gives it its identity – and how it’s supposed to work.


But over time, the epigenome begins to lose information, as happens to CDs due to scratches, and cells lose the ability to turn on the right genes at the right time. That is, they lose their job.


There is no law in biology that says we should age. We don’t know how to stop this, but we are making progress in slowing it down. And in the lab, we’ve been able to reverse the process.

What I want to say is that the epigenome is mutable.


The way we live our lives has a huge impact on those scratches on the CD. Doing things right can significantly slow down the aging process, and today we can measure that clock, we have blood and saliva tests for that.


We’ve found in animals like rats and mice, and even whales and elephants, and people with different lifestyles, that aging can occur at very different rates. And that more than 80 percent of your future health depends on how you live, not on your DNA.


There are things that scientists have discovered by observing people who live long. This includes eating the right types of food (a good place to start is the Mediterranean diet), eating fewer calories, and eating less food. Physical exercise also helps.


There are those who believe that changing the body temperature with ice and cold water is beneficial in this regard.


The reason why scientists believe these lifestyle habits and interventions are effective is that they boost the body’s natural defenses against disease and aging.


Feeling hot or cold, hunger and shortness of breath are ways to activate these defenses. At the root of these defenses are a handful of genes, and we have studied a group of them that control the epigenome and are activated by exercise and starvation.


That is why we believe that eating the right foods and fasting may slow down aging. Aging is the cause of most diseases; They are the leading cause of heart disease, Alzheimer’s disease and diabetes. So the idea is that these habits make you stronger and live longer.


A recent study published in the journal  Nature  Until there is a constant rate of aging in Mammals, but this interferes with your work and indicates that we cannot slow or stop aging?


200 years ago, the maximum speed a human could travel was the speed of a horse. There are techniques we can use to overcome our biological makeup. Technology solves problems and makes us better than before. We are beings who innovate, and we would not have survived without technology. This is what we have been doing for over a million years and we will discover other techniques to overcome it. This is the next step in overcoming the limits of our health that we have inherited. We do this every day, when we take aspirin or get dressed, we are practically changing our environment and we can also change our body chemistry.